MEVAC™ HB1+H120

Combating Newcastle Disease and Infectious Bronchitis in Poultry

Respiratory diseases are among the most devastating challenges in the poultry industry; in most cases, these are the result of more than one pathogen involved. Among several avian viruses with tropism of the respiratory tract, Infectious Bronchitis virus (IBV) and Newcastle disease virus (NDV) are the most important agents compromising poultry health worldwide.¹

Due to the single stranded nature of their genome, these two viruses are able to evolve rapidly, leading to high genetic variability in circulating virus strains. This is even more pronounced in the case of IB, where recombination contributes to genetic variation. IB and ND affect poultry birds of all ages and breeds, but the degree of disease varies based on the age of the birds, with IB being more severe in young chicks, while the severity of ND is more pronounced in chickens of all ages.²

Use MEVAC™ HB1+H120 to strengthen respiratory integrity in your operation. 

Product Description

Storage Precautions

• Store and transport refrigerated (+2°C to +8°C). 
• Do not freeze.
• Store in a dry place protected from direct sunlight.
• Do not use this product after the expiry date.
• Shelf life after first opening the bottle: 3 hours.

Vaccine Preparation

• Vaccine shall be reconstituted with sterile water free from disinfectant and/or antiseptic.
• Shake the reconstituted lyophilisate until complete resuspension before administration.
• Do not administer less than the recommended dosage.
• Read instructions for appropriate dilution.

Withdrawals

Zero days.

Administration

The vaccine should be administered via the eye drop, spray, or drinking water routes.

• Eye drop: For 1,000 birds, reconstitute 1,000 doses into 3 to 5 ml of non-chlorinated drinking water and subsequently dilute it into 30- 50 ml of non-chlorinated drinking water. Use a calibrated dropper to distribute 30-50 μl-drops. Place one drop of the vaccine solution on the eye of each bird, allow the drop to spread, and release the bird.
• Spray vaccination: For 1,000 birds, spray the vaccine solution above the birds using a spray capable of producing micro-droplets (mean diameter 80-100 μm). Make sure that birds are closely confined together during spraying. The ventilation system of the poultry house should be inoperative during the spray administration.
• Drinking water: For 1,000 birds, reconstitute the lyophilisate pellet corresponding to 1,000 doses into 3 to 5 ml of non-chlorinated drinking water and subsequently dilute it into the volume of non-chlorinated drinking water to be consumed within two hours.

Presentation

MEVAC™ HB1 + H120 is packed and presented in vials containing a lyophilisate pellet for reconstitution (1000 doses).

References

1. Swayne DE, Suarez DL. Highly pathogenic avian influenza. Rev Sci Tech. 2000 Aug;19(2):463-82. doi: 10.20506/rst.19.2.1230. PMID: 10935274.

2. The Center for Food Security and Public Health, November 2015, Avian Influenza Fowl Plague, Grippe Aviaire

3. A. Anis, M. AboElkhair, M. Ibrahim, Characterization of highly pathogenic avian influenza H5N8 virus from Egyptian domestic waterfowl in 2017, Avian Pathol. (2018), https://doi.org/10.1080/03079457.2018.1470606

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