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MEVAC™ LSD

Product Overview

MEVAC™ LSD is a live attenuated monovalent vaccine for immunization of cattle against Lumpy Skin Disease virus.

Target Species

Cattle.

Transboundry Control Ruminant

The Impact of Lumpy Skin Disease in Cattle

Lumpy skin disease (LSD) is a poxvirus disease of cattle characterized by fever, nodules on the skin, mucous membranes and internal organs, emaciation, enlarged lymph nodes, oedema of the skin, and sometimes death.1 It is a vector transmitted disease which can spread fast and invade surrounding areas, as far as 7.3 kilometers per week.2

Due to its rapid transboundary spread and substantial economic impact, LSD is listed by WOAH (formerly known as OIE) as notifiable disease.3 LSD is an economically important disease of cattle and can produce a chronic debility in infected animals comparable to that caused by foot and mouth disease (FMD).4

Consistent results under field conditions demonstrated that mass vaccination with live homologous vaccines can lead to a reduction of monthly cases by 99.4%.5 Use MEVAC™ LSD to combat Lumpy Skin Disease in your cattle operation.

Product Details

Composition

  • Live attenuated lumpy skin disease virus (Neethling strain) ≥ 103.5 TCID50 /dose.

Indications

For immunization of cattle against Lumpy Skin Disease virus infection.

Immunity

  • Onset of immunity: 10 days after vaccination; animals are fully protected after 21 days.
  • Duration of immunity: at least 1 year.

Vaccination Program

Animals can be vaccinated from early age, as per advice from your veterinarian.

  • Primary Vaccination:
    • Cattle: all adult animals should be vaccinated.
    • Calves from vaccinated cows: at 3 months.
    • Calves from unvaccinated cows: at any age.
  • Booster Vaccination:
    • Annual vaccination. It is preferable to vaccinate the animals before the risk period (e.g. early spring).
  • Emergency Cases:
    • Vaccinated animals should be boosted with MEVAC™ LSD after 5-6 months from the primary vaccination to increase the vaccination coverage.
MEVAC™ LSD

Withdrawal

Zero days. 

Considerations

  • Swelling at the injection site may occur in very rare cases and usually resolve without treatment.
  • A temporary decrease in milk production may occur in very rare cases.
  • Can be used during pregnancy (safe during all stages of pregnancy).

Dosage

Cattle: 1 mL per animal via subcutaneous injection, to be applied in the area of the neck.

Administration

  • The vaccine must be reconstituted with the provided sterile diluent.
  • Using a single-use sterile syringe (3 mL; 16-gauge needle; ¾ inches), transfer about 2-3 mL of sterile diluent to the vial containing the vaccine.
  • Mix thoroughly until the vaccine is dissolved.
  • Transfer the suspension back to the remaining sterile diluent and mix well again.
  • Shake the vial before filling the syringe.
  • Use sterile injection equipment.
  • Use the entire contents when first opened.

Storage Precautions

  • Store and transport refrigerated (+2°C to +8°C).
  • Do not freeze.
  • Store in a dry place protected from direct light.
  • Do not use this product after the expiry date.
  • Shelf life: 24 months after manufacturing date.
  • Shelf life after reconstitution according to directions: 3 hours.

Presentation

MEVAC™ LSD is packed and presented in vials containing a lyophilisate pellet for reconstitution (10, 25, 50 doses).

Download the Product Information Sheet

MEVAC LSD product information sheet
Download

References

1. OIE terrestrial manual 2017 chapter 2.4.13

2. Mercier et al., 2018, Spread rate of lumpy skin disease in the Balkans, 2015–2016

3. S. Babiuk et al, Capripoxviruses: An Emerging Worldwide Threat to Sheep, Goats and Cattle.

4. Dr F. Glyn Davies, Lumpy skin disease of cattle: A growing problem in Africa and the Near East, FAO.

5. LSD cattle disease cases decrease sharply this year, The Nation Thailand, Sept 2022 https://www.nationthailand.com/in-focus/ national/40019616

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The content on this site is intended for informational purposes only and is not intended to be a substitute for professional veterinary advice. Although the information on this site is accessible worldwide, not all products or services are available to all persons or in all geographic locations or jurisdictions. Certain statements, product labeling and claims may differ by geography or as required by local governmental regulations.