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References:
- Salminen, et al. Nat rev Gastroenterol Hepatol (2022). https://www.nature.com/articles/s41575-021-00440-6
- Evans, M., et al., Effect of a Euglena gracilis Fermentate on Immune Function in Healthy, Active Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients, 2019, 11(12), 2926
- Kemin, BetaVia Complete can prime key cells in the innate immune system. KHTL-017-150.
- KHTL-017-162 BetaVia Pure Can Prime Key Cell sin the Innate Immune system. KHTL-017-150.
- KHTL-017-160 Paramylon Improves Antioxidant Status and Metabolic Health-TL-20-18529
- KHTL-017-149 Characteristics and Prebiotic like Properties of BetaVia Complete
- Kemin, Characteristics and prebiotic like properties of BetaVia Complete. KHTL-017-149.
- Bhattad T, Koradiya A, Prakash G. Prebiotic activity of paramylon isolated from heterotrophically grown Euglena gracilis. Heliyon. 2022 Aug 27;7 (9): e07884. doi: 10.1016/j.heliyon.2022.e07884
- Russo, R., et al. “Euglena gracilis paramylon activates human lymphocytes by upregulating pro-inflammatory factors.” Food Science & Nutrition 5.2 (2017): 205-214
- Kondo, Y., et al. "Cytokine-related immunopotentiating activities of Paramylon, a β-(1→ 3)-D-glucan from Euglena gracilis." Journal of Pharmacobio-dynamics 15.11 (1992): 617-621.
- Kankkunen, P., et al. "(1, 3)-β-Glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages." The Journal of Immunology 184.11 (2010): 6335-6342
- Brown, G.D., and Siamon G. Immune recognition: A new receptor for [beta]-glucans." Nature 413.6851 (2001): 36.
- Brown, G.D., et al. "Dectin-1 is a major β-glucan receptor on macrophages. Journal of Experimental Medicine 196.3 (2002): 407-412.
- Brown, G.D., et al. Dectin-1 mediates the biological effects of β-glucans." Journal of Experimental medicine 197.9 (2003): 1119-1124.
- Goodridge, H.S. et al. "β‐glucan recognition by the innate immune system. Immunological reviews 230.1 (2009): 38-50.
- KEMIN internal document: SD-18-00083
- Ishibashi, Ken-ichi, et al. “Effects of Euglena gracilis EOD-1 ingestion on salivary IgA reactivity and health-related quality of life in humans.” Nutrients 11.5 (2019): 1144.
- Nakashima, Ayaka, et al. “The alga Euglena gracilis stimulates Faecalibacterium in the gut and contributes to increased defecation.” Scientific reports 11.1 (2021): 1-8.
- Nakashima, Ayaka, et al. “Effects of Euglena gracilis Intake on Mood and Autonomic Activity under Mental Workload, and Subjective Sleep Quality: A Randomized, Double-Blind, Placebo-Controlled Trial.” Nutrients 12.11 (2020): 3243.
- Kawano, Takanori, et al. “Effect of Food Containing Paramylon Derived from Euglena gracilis EOD-1 on Fatigue in Healthy Adults: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Trail.” Nutrients 12.10 (2020): 3098.
- SD-17-00243 Kemin Internal Document (Effect of 50%BG on the immune and intestinal health status of weaned piglets)
- SD-9-21271 Kemin Internal Document (Effect of 50% BG on IgA in piglet feces)
- TD-17-0322 Kemin Internal Document (Effect of 50% and 95% BG on gut and systemic immunity in mice)