MEVAC™ PPR

The Impact of Peste des Petits Ruminants in Goat and Sheep

Peste des Petits Ruminants (PPR) is a viral disease, caused by a morbillivirus closely related to rinderpest virus, which affects goats, sheep, and some wild relatives of domesticated small ruminants, as well as camels. It was first reported in Ivory Coast in 1942. It is characterised by severe morbidity and mortality rates, and has a high economic impact in areas of Africa, the Middle East, and Asia, where small ruminants contribute to guaranteeing livelihoods.¹

Affected animals present high fever and depression, along with eye and nose discharges. Animals cannot eat, as the mouth becomes covered in painful erosive lesions and the animals suffer from severe pneumonia and diarrhoea. Death is frequently the outcome.¹

PPR is an WOAH-listed disease and must be reported to the WOAH , according to the Terrestrial Animal Health Code. Countries have the possibility to apply for the official recognition by the WOAH of their freedom from PPR for their whole country or for a zone, and for the endorsement of their national official control programme for PPR.¹

Together, WOAH and the FAO developed the Global Control and Eradication Strategy of PPR and have set the goal of eradicating the disease by 2030. Commercial PPR vaccines have demonstrated life-long protective immunity in vaccinated animals, therefore represent a core pillar in the control strategy.¹

Product Details

Administration

• Shake the reconstituted lyophilisate until complete resuspension.
• Transfer the suspension back to the remaining sterile diluent and mix well again.
• Rinse the vaccine vial by transferring some of the diluent once more from the container containing the diluent. Pour this liquid back into the diluent container.
• Shake well before filling the syringe allotted for administration.
• Use a sterile syringe (16-gauge needle; ½ inch) for injection.
• The needle used to withdraw the vaccine from the vial should not be used for injection.
• Keep the vial of the reconstituted vaccine in an ice bath.
• Use the entire contents when first opened.
• The reconstituted vaccine should not be exposed to direct light and high temperatures.
• Do not administer less than the recommended dose.
• Disinfectants and antiseptics should never be used for disinfecting syringes and needles used in vaccination.

Storage Precautions

• Store and transport refrigerated (+2°C to +8°C).
• Do not freeze.
• Store in a dry place protected from direct light.
• Do not use this product after the expiry date.
• Shelf life: 24 months after manufacturing date.
• Shelf life after reconstitution according to directions: 3 hours.

Presentation

MEVAC™ PPR is packed and presented in a cardboard box containing 10 glass vials of 6 ml. Contents per vial: 25, 50, or 100 doses. The sterile diluent is packed and presented in polyethylene terephthalate (PET) bottles of 25, 50, or 100 mL.

References

1. WOAH (2021). https://www.woah.org/en/disease/peste-des-petits-ruminants/

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